Protein kinase function of pyruvate kinase M2 and cancer
Abstract Pyruvate kinase is a terminal enzyme in the glycolytic pathway, where it catalyzes the conversion of phosphoenolpyruvate to pyruvate and production of ATP via substrate level phosphorylation. PKM2 is one of four isoforms of pyruvate kinase and is widely expressed in many types of tumors and...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2020-10-01
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| Col·lecció: | Cancer Cell International |
| Matèries: | |
| Accés en línia: | http://link.springer.com/article/10.1186/s12935-020-01612-1 |
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