Reactive pericytes in early phase are involved in glial activation and late-onset hypersusceptibility to pilocarpine-induced seizures in traumatic brain injury model mice

In this study, among neurovascular unit (NVU) cells, we focused on pericyte reactivity in mice subjected to controlled cortical impact (CCI) to understand how traumatic brain injury (TBI) causes uncoordinated crosstalk in the NVU and alters neuronal activity. Histological analyses of brain pericytes...

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Hlavní autoři:	Kenta Sakai, Fuyuko Takata, Gaku Yamanaka, Miho Yasunaga, Kana Hashiguchi, Kazuki Tominaga, Kouichi Itoh, Yasufumi Kataoka, Atsushi Yamauchi, Shinya Dohgu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2021-01-01
Edice:	Journal of Pharmacological Sciences
Témata:	Traumatic brain injury Reactive pericytes PDGFRβ Imatinib Microglia
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1347861320301146
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