YBX1-LDHB axis orchestrates pyruvate production from lactate to promote ICC initiation and development

Previous work from our group established that Y-box binding protein 1 (YBX1) plays a pivotal role in the initiation and progression of intrahepatic cholangiocarcinoma (ICC); however, its specific biological functions and underlying regulatory mechanisms remain unclear. The current study demonstrates...

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Главные авторы:	Yong Liu, Fei Wang, Mi Zhang, Xiabing Shi, Lei Li, Tingjie Wang, Haifeng Zhang, Zhongyu Cheng, Xiangpan Li, Juan Chen, Chuanrui Xu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2026-02-01
Серии:	Pharmacological Research
Предметы:	Intrahepatic cholangiocarcinoma YBX1 LDHB Lactate TCA cycle
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S1043661826000253
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