Mathematical modeling of the molecular switch of TNFR1-mediated signaling pathways applying Petri net formalism and in silico knockout analysis.
The paper describes a mathematical model of the molecular switches of cell survival, apoptosis, and necroptosis in cellular signaling pathways initiated by tumor necrosis factor 1. Based on experimental findings in the literature, we constructed a Petri net model based on detailed molecular reaction...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science (PLoS)
2022-08-01
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| سلاسل: | PLoS Computational Biology |
| الوصول للمادة أونلاين: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010383&type=printable |
| الوسوم: |
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