Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing

Abstract The Oxford Nanopore (ONT) platform provides portable and rapid genome sequencing, and its ability to natively profile DNA methylation without complex sample processing is attractive for point-of-care real-time sequencing. We recently demonstrated ONT shallow whole-genome sequencing to detec...

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Autori principali:	Efrat Katsman, Shari Orlanski, Filippo Martignano, Ilana Fox-Fisher, Ruth Shemer, Yuval Dor, Aviad Zick, Amir Eden, Iacopo Petrini, Silvestro G. Conticello, Benjamin P. Berman
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2022-07-01
Serie:	Genome Biology
Accesso online:	https://doi.org/10.1186/s13059-022-02710-1
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