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Conformational Heterogeneity of the HIV Envelope Glycan Shield

Abstract To better understand the conformational properties of the glycan shield covering the surface of the HIV gp120/gp41 envelope (Env) trimer, and how the glycan shield impacts the accessibility of the underlying protein surface, we performed enhanced sampling molecular dynamics (MD) simulations...

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Bibliografiske detaljer
Principais autores: Mingjun Yang, Jing Huang, Raphael Simon, Lai-Xi Wang, Alexander D. MacKerell
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2017-06-01
Serier:Scientific Reports
Online adgang:https://doi.org/10.1038/s41598-017-04532-9
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