Computational fragment-based binding site identification by ligand competitive saturation.
Fragment-based drug discovery using NMR and x-ray crystallographic methods has proven utility but also non-trivial time, materials, and labor costs. Current computational fragment-based approaches circumvent these issues but suffer from limited representations of protein flexibility and solvation ef...
Na minha lista:
| Principais autores: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2009-07-01
|
| Serier: | PLoS Computational Biology |
| Online adgang: | http://europepmc.org/articles/PMC2700966?pdf=render |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|