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Challenges in implementing model-based phase I designs in a grant-funded clinical trials unit

Abstract Background For a clinical trials unit to run its first model-based, phase I trial, the statistician, chief investigator, and trial manager must all acquire a new set of skills. These trials also require a different approach to funding and data collection. Challenges and discussion From the...

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Principais autores: Eleni Frangou, Jane Holmes, Sharon Love, Naomi McGregor, Maria Hawkins
格式: Artigo
語言:Inglês
出版: BMC 2017-12-01
叢編:Trials
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在線閱讀:http://link.springer.com/article/10.1186/s13063-017-2389-2
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