The alphaherpesvirus gE/gI glycoprotein complex and proteases jointly orchestrate invasion across the host’s upper respiratory epithelial barrier

ABSTRACT Alphaherpesviruses, including herpes simplex virus type 1 (HSV-1), pseudorabies virus (PRV), and bovine herpesvirus type 1 (BoHV-1), are significant pathogens affecting humans and animals. These viruses penetrate the upper respiratory tract mucosa, yet the mechanisms facilitating this invas...

Полное описание

Библиографические подробности

Главные авторы:	E. Van Crombrugge, X. Ren, S. Glorieux, I. Zarak, W. Van den Broeck, C. Bachert, N. Zhang, T. Van Zele, D. Kim, G. A. Smith, K. Laval, H. Nauwynck
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology 2024-11-01
Серии:	mBio
Предметы:	alphaherpesvirus upper respiratory tract pathogenesis, mucosa invasion gE/gI complex proteases urokinase plasminogen activator
Online-ссылка:	https://journals.asm.org/doi/10.1128/mbio.01873-24
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!