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Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia

Neonatal cerebral hypoxia-ischemia (HI) is the leading cause of death and disability in newborns with the only current treatment being hypothermia. An increased understanding of the pathways that facilitate tissue repair after HI may aid the development of better treatments. Here, we study the role...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Lauritz Kennedy, Emilie R Glesaaen, Vuk Palibrk, Marco Pannone, Wei Wang, Ali Al-Jabri, Rajikala Suganthan, Niklas Meyer, Marie Landa Austbø, Xiaolin Lin, Linda H Bergersen, Magnar Bjørås, Johanne E Rinholm
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2022-08-01
Schriftenreihe:eLife
Schlagworte:
lactate
hcar1
hca1
gpr81
ischemia
neurogenesis
Online-Zugang:https://elifesciences.org/articles/76451
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