Influence of Mutations and N-Glycosylation Sites in the Receptor-Binding Domain (RBD) and the Membrane Protein of SARS-CoV-2 Variants of Concern on Antibody Binding in ELISA

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect human cells by first attaching to the ACE-2 receptor via its receptor-binding domain (RBD) in the spike protein. Here, we report the influence of N-glycosylation sites of the RBD and the membrane (M) protein on IgG antibody bind...

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Главные авторы:	Mandy Schwarze, Daniela Volke, Juan Camilo Rojas Echeverri, Robin Schick, Nicole Lakowa, Thomas Grünewald, Johannes Wolf, Stephan Borte, Markus Scholz, Andor Krizsan, Ralf Hoffmann
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2024-03-01
Серии:	Biology
Предметы:	ELISA epitope immunoglobulins G (IgG) glycan mapping N-glycosylation SARS-CoV-2
Online-ссылка:	https://www.mdpi.com/2079-7737/13/4/207
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