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The genetics and epidemiology of N- and O-immunoglobulin A glycomics

Abstract Background Immunoglobulin (Ig) glycosylation modulates the immune response and plays a critical role in ageing and diseases. Studies have mainly focused on IgG glycosylation, and little is known about the genetics and epidemiology of IgA glycosylation. Methods We generated, using a novel li...

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Huvudupphov: Alessia Visconti, Niccolò Rossi, Albert Bondt, Agnes Hipgrave Ederveen, Gaurav Thareja, Carolien A. M. Koeleman, Nisha Stephan, Anna Halama, Hannah J. Lomax-Browne, Matthew C. Pickering, Xu-jie Zhou, Manfred Wuhrer, Karsten Suhre, Mario Falchi
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2024-08-01
Serie:Genome Medicine
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Länkar:https://doi.org/10.1186/s13073-024-01369-6
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