Substance P Increases the Excitability of Dorsal Motor Nucleus of the Vagus Nerve via Inhibition of Potassium Channels

Increases in the substance P (SP) concentration in the medial portion of the dorsal motor nucleus of the vagus nerve (mDMV) in the brainstem are closely associated with chemotherapy induced nausea and vomiting (CINV). However, the underlying cellular and molecular mechanisms of action are not well u...

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Principais autores:	Eunhee Yang, Woojin Kim, Yong Seek Park, Young-Ho Jin
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2022-04-01
叢編:	Frontiers in Neuroscience
主題:	chemotherapy nausea and vomiting neurokinin receptor acid-sensitive potassium channel leak potassium channel substance P
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fnins.2022.867831/full
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