Substance P Increases the Excitability of Dorsal Motor Nucleus of the Vagus Nerve via Inhibition of Potassium Channels

Increases in the substance P (SP) concentration in the medial portion of the dorsal motor nucleus of the vagus nerve (mDMV) in the brainstem are closely associated with chemotherapy induced nausea and vomiting (CINV). However, the underlying cellular and molecular mechanisms of action are not well u...

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Ngā kaituhi matua:	Eunhee Yang, Woojin Kim, Yong Seek Park, Young-Ho Jin
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2022-04-01
Rangatū:	Frontiers in Neuroscience
Ngā marau:	chemotherapy nausea and vomiting neurokinin receptor acid-sensitive potassium channel leak potassium channel substance P
Urunga tuihono:	https://www.frontiersin.org/articles/10.3389/fnins.2022.867831/full
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!