Inhibitors of HIV-1 Reverse Transcriptase—Associated Ribonuclease H Activity
HIV-1 enzyme reverse transcriptase (RT) is a major target for antiviral drug development, with over half of current FDA-approved therapeutics against HIV infection targeting the DNA polymerase activity of this enzyme. HIV-1 RT is a multifunctional enzyme that has RNA and DNA dependent polymerase act...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2012-10-01
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| Schriftenreihe: | Biology |
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| Online-Zugang: | http://www.mdpi.com/2079-7737/1/3/521 |
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