Inhibitors of HIV-1 Reverse Transcriptase—Associated Ribonuclease H Activity

HIV-1 enzyme reverse transcriptase (RT) is a major target for antiviral drug development, with over half of current FDA-approved therapeutics against HIV infection targeting the DNA polymerase activity of this enzyme. HIV-1 RT is a multifunctional enzyme that has RNA and DNA dependent polymerase act...

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Principais autores:	Michael A. Parniak, Stefan G. Sarafianos, Rieko Ishima, Krystal LaBarge, Tatiana Ilina
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2012-10-01
叢編:	Biology
主題:	HIV-1 reverse transcription ribonuclease H (RNase H) ribonuclease H inhibitor (RNHI)
在線閱讀:	http://www.mdpi.com/2079-7737/1/3/521
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