EP9158H: An Immunoinformatics-Designed mRNA Vaccine Encoding Multi-Epitope Antigens and Dual TLR Agonists for Tuberculosis Prevention

<b>Background</b>: Tuberculosis (TB) remains a pressing global health crisis. The inadequate efficacy of the BCG vaccine against adult pulmonary TB underscores the urgent need for novel, effective vaccines. This study aimed to design a novel mRNA vaccine candidate against TB using a rational immunoi...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Mingming Zhang, Syed Luqman Ali, Yuan Tian, Aigul Abduldayeva, Shuang Zhou, Yajing An, Yufeng Li, Ruizi Ni, Lingxia Zhang, Yanhua Liu, Weiguo Sun, Wenping Gong
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2025-12-01
Σειρά:	Bioengineering
Θέματα:	tuberculosis mRNA vaccine immunoinformatics TLR agonist molecular dynamics immune simulation
Διαθέσιμο Online:	https://www.mdpi.com/2306-5354/12/12/1378
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