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Divergent biological pathways distinguish community-acquired pneumonia from COVID-19 despite similar plasma cytokine profiles

Abstract Background Pulmonary infections, ranging from mild respiratory issues to severe multiorgan failure, pose a major global health threat. The immune response in community-acquired pneumonia (CAP) and COVID-19 influences disease severity and outcomes, but molecular pathogenesis differs across p...

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Principais autores: Douglas D. Fraser, Logan R. Van Nynatten, David Tweddell, Mark Daley, James A. Russell, CAPtivate Consortium
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-08-01
Serier:Respiratory Research
Fag:
Community acquired pneumonia (CAP)
COVID-19
Cytokines
Biomarkers
Proteomics
Machine learning
Online adgang:https://doi.org/10.1186/s12931-025-03331-5
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