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Differential protein expression and enriched pathways in pediatric sepsis: identification of novel brain-associated biomarkers revealed through proteomic profiling

Abstract Background Sepsis, defined by confirmed or suspected infection with systemic inflammatory response syndrome, requires robust biomarker identification. Proteomics enables protein quantification and expression analysis across disease states. This study investigated differential protein expres...

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Autors principals: Vincenzo Stranges, David Tweddell, Enis Cela, Maria Morello, Mark Daley, Gediminas Cepinskas, Douglas D. Fraser
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-11-01
Col·lecció:Molecular Medicine
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Accés en línia:https://doi.org/10.1186/s10020-025-01397-x
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