Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans.

The intracellular level of fatty aldehydes is tightly regulated by aldehyde dehydrogenases to minimize the formation of toxic lipid and protein adducts. Importantly, the dysregulation of aldehyde dehydrogenases has been implicated in neurologic disorder and cancer in humans. However, cellular respon...

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Bibliografiske detaljer

Principais autores:	Lidan Zeng, Xuesong Li, Christopher B Preusch, Gary J He, Ningyi Xu, Tom H Cheung, Jianan Qu, Ho Yi Mak
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2021-07-01
Serier:	PLoS Genetics
Online adgang:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009635&type=printable
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