TRIM8 Blunts the Pro-proliferative Action of ΔNp63α in a p53 Wild-Type Background

The p53 gene family network plays a pivotal role in the control of many biological processes and therefore the right balance between the pro-apoptotic and pro-survival isoforms is key to maintain cellular homeostasis. The stability of the p53 tumor suppressor protein and that of oncogenic ΔNp63α, is...

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Bibliografiske detaljer

Principais autores:	Mariano Francesco Caratozzolo, Flaviana Marzano, Daniela Isabel Abbrescia, Francesca Mastropasqua, Vittoria Petruzzella, Viola Calabrò, Graziano Pesole, Elisabetta Sbisà, Luisa Guerrini, Apollonia Tullo
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2019-11-01
Serier:	Frontiers in Oncology
Fag:	TRIM8 p53 ΔNp63α chemoresistant tumors caspase-1 proteasome
Online adgang:	https://www.frontiersin.org/article/10.3389/fonc.2019.01154/full
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