Aberrant Phase Separation of FUS Leads to Lysosome Sequestering and Acidification
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that leads to the death of upper and lower motor neurons. While most cases of ALS are sporadic, some of the familial forms of the disease are caused by mutations in the gene encoding for the RNA-binding protein FUS. Under...
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| Váldodahkkit: | , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Frontiers Media S.A.
2021-10-01
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| Ráidu: | Frontiers in Cell and Developmental Biology |
| Fáttát: | |
| Liŋkkat: | https://www.frontiersin.org/articles/10.3389/fcell.2021.716919/full |
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