New insights on microglial lysosomal acidification: A therapeutic target of neurodegenerative diseases

Background: Microglia, the resident immune cells of the central nervous system (CNS), maintain brain homeostasis and respond to pathological insults. Microglial dysfunction has been implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disea...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Ravindran Jaganathan, Srilakshmi Vijayakumar, Yinchi Chen, Jiaxi Ye, Pugazhandhi Bakthavatchalam, Dapkupar Wankhar, Chuanbin Yang, Ashok Iyaswamy, Min Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-10-01
coleção:	Neurobiology of Disease
Assuntos:	Lysosomal acidification Neurodegenerative diseases Lysosomal pH Microglia Dysfunctional lysosomes
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996126003001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!