Antimicrobial Peptide Reverses ABCB1-Mediated Chemotherapeutic Drug Resistance

Multidrug resistance (MDR) of tumor cells to chemotherapeutic agents is the main reason for the failure of cancer chemotherapy. Overexpression of ABCB1 transporter that actively pumps various drugs out of the cells has been considered a major contributing factor for MDR. Over the past decade, many a...

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Hlavní autoři:	Xiaofang Luo, Qiu-Xu Teng, Jin-Yun Dong, Dong-Hua Yang, Meifeng Wang, Wubliker Dessie, Jiang-Jiang Qin, Zi-Ning Lei, Jing-Quan Wang, Zuodong Qin, Zhe-Sheng Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-08-01
Edice:	Frontiers in Pharmacology
Témata:	multidrug resistance ABC transporter antimicrobial peptide HX-12C reversal agents combination therapy
On-line přístup:	https://www.frontiersin.org/article/10.3389/fphar.2020.01208/full
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