Small molecule KDM4s inhibitors as anti-cancer agents
Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone. Among these enzymes, KDM4s are one subfamily of JmjC KDMs and play important roles in both normal and cancer cells. The disc...
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| Автори: | , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Taylor & Francis Group
2018-01-01
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| Серія: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Предмети: | |
| Онлайн доступ: | http://dx.doi.org/10.1080/14756366.2018.1455676 |
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