Novel PLEC-EML4-ALK Double Fusion Underlying Crizotinib Resistance in a Metastatic Inflammatory Myofibroblastic Tumor: A Case Report

ALK fusions are frequent oncogenic drivers in inflammatory myofibroblastic tumors. Treatment with crizotinib is effective in fusion-positive patients; however, acquired resistance remains a challenge. Here, we present a case of EML4-ALK-positive metastatic inflammatory myofibroblastic tumor that ini...

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主要な著者:	Alessandra Maleddu, MD, Trista K. Hinz, MS, Margaret A. Black, MD, Dara L. Aisner, MD, PhD, Carrie B. Marshall, MD, Anthony D. Elias, MD, Breelyn A. Wilky, MD, Lynn E. Heasley, PhD, Kurtis D. Davies, PhD
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2025-05-01
シリーズ:	JTO Clinical and Research Reports
主題:	Case report ALK fusion Crizotinib Inflammatory myofibroblastic tumor
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2666364325000074
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