Negative auto-regulation of myostatin expression is mediated by Smad3 and microRNA-27.

Growth factors, such as myostatin (Mstn), play an important role in regulating post-natal myogenesis. In fact, loss of Mstn has been shown to result in increased post-natal muscle growth through enhanced satellite cell functionality; while elevated levels of Mstn result in dramatic skeletal muscle w...

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Detalhes bibliográficos

Principais autores:	Craig McFarlane, Anuradha Vajjala, Harikumar Arigela, Sudarsanareddy Lokireddy, XiaoJia Ge, Sabeera Bonala, Ravikumar Manickam, Ravi Kambadur, Mridula Sharma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2014-01-01
coleção:	PLoS ONE
Acesso em linha:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24498167/?tool=EBI
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