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Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy

Loss of innervation is a key driver of age associated muscle atrophy and weakness (sarcopenia). Our laboratory has previously shown that denervation induced atrophy is associated with the generation of mitochondrial hydroperoxides and lipid mediators produced downstream of cPLA2 and 12/15 lipoxygena...

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Principais autores: Jacob L. Brown, Fredrick F. Peelor, III, Constantin Georgescu, Jonathan D. Wren, Michael Kinter, Victoria J. Tyrrell, Valerie B. O'Donnell, Benjamin F. Miller, Holly Van Remmen
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2022-11-01
Serija:Redox Biology
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2213231722002907
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