Docosahexaenoic (DHA) modulates phospholipid-hydroperoxide glutathione peroxidase (Gpx4) gene expression to ensure self-protection from oxidative damage in hippocampal cells

Docosahexaenoic acid (DHA, 22:6n-3) is a unique polyunsaturated fatty acid particularly abundant in nerve cell membrane phospholipids. DHA is a pleiotropic molecule that, not only modulates the physicochemical properties and architecture of neuronal plasma membrane, but it is also involved in multi...

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Principais autores:	Veronica eCasañas-Sanchez, José Antonio Pérez, Noemi eFabelo, David eQuinto-Alemany, Mario L Diaz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2015-07-01
coleção:	Frontiers in Physiology
Assuntos:	Neuroprotection Transcriptional regulation docosahexaenoic acid glutathione peroxidase 4 Intron retention hippocampal cells
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00203/full
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