Mutations in active surface sites of NtGGPPS1 enhance carotenoid biosynthesis and drought resistance in Nicotiana tabacum

Abstract Background Amino acids on the surface of enzymes play a vital role in their catalytic activity and functional properties, influencing enzymatic stability and inducing conformational changes. Results In this research, we demonstrate that surface mutations in geranylgeranyl diphosphate syntha...

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Autores principales:	Shanshan Song, Yulong Gao, Puqing Fan, Faming Lin, Houliang Zhou, Zhiyang Li, Hang Liu, Hongyi Su, Qiang Zhong, Zhuonan Liu, Xinru Ren, Xiaoran Wang, Yongchun Shi, Yu Zhang, Xiaoquan Zhang, Ran Wang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-10-01
Colección:	BMC Plant Biology
Materias:	Rational design Carotenoid Drought tolerance Geranylgeranyl diphosphate synthase (GGPPS) Surface site
Acceso en línea:	https://doi.org/10.1186/s12870-025-07337-5
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