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Deep response to a combination of mTOR inhibitor temsirolimus and dual immunotherapy of nivolumab/ipilimumab in poorly differentiated thyroid carcinoma with PTEN mutation: a case report and literature review

Treating advanced thyroid cancer presents challenges due to its resistance to various treatment modalities, thereby limiting therapeutic options. To our knowledge, this study is the first to report the efficacy of temsirolimus in conjunction with dual immunotherapy of nivolumab/ipilimumab to treat h...

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Uloženo v:
Hlavní autoři: Youjin Oh, Joo Hee Park, Trie Arni Djunadi, Zunairah Shah, Liam Il-Young Chung, Young Kwang Chae
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-01-01
Edice:Frontiers in Endocrinology
Témata:
poorly differentiated thyroid carcinomas
mTOR inhibitors
immunotherapy
treatment outcomes
case report
On-line přístup:https://www.frontiersin.org/articles/10.3389/fendo.2024.1304188/full
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