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The Cytoprotective and Cytotoxic Functions of Autophagy in Response to mTOR Inhibitors

The inhibitors of mammalian target of rapapmycin (mTOR), everolimus, temsirolimus and rapamycin, have a wide range of clinical utility; however, as is inevitably the case with other chemotherapeutic agents, resistance development constrains their effectiveness. One putative mechanism of resistance i...

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Bibliografische Detailangaben
Hauptverfasser: Ahmed M. Elshazly, Aya A. Elzahed, David A. Gewirtz
Format: Artigo
Sprache:Inglês
Veröffentlicht: IMR Press 2024-06-01
Schriftenreihe:Frontiers in Bioscience-Landmark
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Online-Zugang:https://www.imrpress.com/journal/FBL/29/6/10.31083/j.fbl2906231
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