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Analysis of global DNA methylation and epigenetic modifiers (DNMTs and HDACs) in human foetal endothelium exposed to gestational and type 2 diabetes

Foetuses exposed to maternal gestational diabetes (GDM) and type 2 diabetes (T2D) have an increased risk of adverse perinatal outcomes. Epigenetic mechanisms, including DNA methylation and histone modifications, may act as mediators of persistent metabolic memory in endothelial cells (ECs) exposed t...

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Principais autores: Samar Sultan, Sultanh AlMalki
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2023-12-01
Serier:Epigenetics
Fag:
endothelial cells
gestational diabetes
type 2 diabetes
dna methylation
epigenetic enzymes
Online adgang:http://dx.doi.org/10.1080/15592294.2023.2201714
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