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Potential therapeutic targets for ischemic stroke in pre-clinical studies: Epigenetic-modifying enzymes DNMT/TET and HAT/HDAC

Ischemic stroke (IS) remains a leading cause of mortality and disability worldwide, driven by genetic predispositions and environmental interactions, with epigenetics playing a pivotal role in mediating these processes. Specific modifying enzymes that regulate epigenetic changes have emerged as prom...

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Wedi'i Gadw mewn:
Prif Awduron: Yurou Guo, Jing Li, Xiaodan Liu, Huang Ding, Wei Zhang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2025-04-01
Cyfres:Frontiers in Pharmacology
Pynciau:
epigenetics
ischemic stroke
DNMT
TET
HAT
HDAC
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fphar.2025.1571276/full
Tagiau: Ychwanegu Tag
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