Enhanced production of mesencephalic dopaminergic neurons from lineage-restricted human undifferentiated stem cells

Abstract Current differentiation protocols for generating mesencephalic dopaminergic (mesDA) neurons from human pluripotent stem cells result in grafts containing only a small proportion of mesDA neurons when transplanted in vivo. In this study, we develop lineage-restricted undifferentiated stem ce...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Muyesier Maimaitili, Muwan Chen, Fabia Febbraro, Ekin Ucuncu, Rachel Kelly, Jonathan Christos Niclis, Josefine Rågård Christiansen, Noëmie Mermet-Joret, Dragos Niculescu, Johanne Lauritsen, Angelo Iannielli, Ida H. Klæstrup, Uffe Birk Jensen, Per Qvist, Sadegh Nabavi, Vania Broccoli, Anders Nykjær, Marina Romero-Ramos, Mark Denham
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2023-12-01
Serija:	Nature Communications
Online dostop:	https://doi.org/10.1038/s41467-023-43471-0
Oznake:	Označite Brez oznak, prvi označite!