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Direct Induction and Functional Maturation of Forebrain GABAergic Neurons from Human Pluripotent Stem Cells

Gamma-aminobutyric acid (GABA)-releasing interneurons play an important modulatory role in the cortex and have been implicated in multiple neurological disorders. Patient-derived interneurons could provide a foundation for studying the pathogenesis of these diseases as well as for identifying potent...

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Principais autores: Alfred Xuyang Sun, Qiang Yuan, Shawn Tan, Yixin Xiao, Danlei Wang, Audrey Tze Ting Khoo, Levena Sani, Hoang-Dai Tran, Paul Kim, Yong Seng Chiew, Kea Joo Lee, Yi-Chun Yen, Huck Hui Ng, Bing Lim, Hyunsoo Shawn Je
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016-08-01
coleção:Cell Reports
Assuntos:
direct conversion
GABA
human pluripotent stem cells
interneuron
synapse
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124716309536
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