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Inhibiting the RNA helicase DDX3X in Burkitt lymphoma induces oxydative stress and impedes tumor progression in xenografts

IntroductionBurkitt Lymphoma (BL), an aggressive B-cell lymphoma driven by MYC translocations, requires intensive chemotherapy treatments which deliver high effectiveness yet increase future risks of developing secondary malignancies. We have previously shown that DDX3X, an RNA helicase frequently m...

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Detaylı Bibliyografya
Asıl Yazarlar: Hugues Beauchemin, Zeinab Dalloul, Eva-Maria Piskor, Virginie Calderon, Andrew Chatr-aryamontri, Thierry Bertomeu, Tarik Möröy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2025-07-01
Seri Bilgileri:Frontiers in Cell and Developmental Biology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fcell.2025.1642006/full
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