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The NuRD component CHD3 promotes BMP signalling during cranial neural crest cell specification

Abstract Pathogenic genetic variants in the NuRD component CHD3 cause Snijders Blok–Campeau Syndrome, a neurodevelopmental disorder manifesting with intellectual disability and craniofacial anomalies. To investigate the role of CHD3 in craniofacial development, we differentiated control and CHD3-dep...

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Autores principales: Zoe H Mitchell, Joery den Hoed, Willemijn Claassen, Martina Demurtas, Laura Deelen, Philippe M Campeau, Karen Liu, Simon E Fisher, Marco Trizzino
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Nature 2025-08-01
Colección:EMBO Reports
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Acceso en línea:https://doi.org/10.1038/s44319-025-00555-w
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