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Assessing the role of the T-box transcription factor Eomes in B cell differentiation during either Th1 or Th2 cell-biased responses.

Successful T-dependent humoral responses require the production of antibody-secreting plasmablasts, as well as the formation of germinal centers which eventually form high-affinity B cell memory. The ability of B cells to differentiate into germinal center and plasma cells, as well as the ability to...

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Bibliografiske detaljer
Principais autores: Lucy Cooper, Lauren Hailes, Amania Sheikh, Colby Zaph, Gabrielle T Belz, Joanna R Groom, Kim L Good-Jacobson
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2018-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0208343
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