Microgravity-driven Rab27B activation amplifies mesenchymal stem cell-derived extracellular vesicle production and functions

Abstract Background Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) are emerging as promising treatments for immunomodulation and tissue regeneration. However, the scalable production of functionally enhanced EVs remains a critical challenge. This study introduces microgravity culture...

Полное описание

Библиографические подробности

Главные авторы:	Yi Ding, Yiru Fu, Meng Sun, Yue Li, Ang Li, Ye Li
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2025-10-01
Серии:	Stem Cell Research & Therapy
Предметы:	Extracellular vesicles Microgravity Rab27B Immunomodulatory Tissue repair and regeneration
Online-ссылка:	https://doi.org/10.1186/s13287-025-04711-w
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!