Reprogramming T cell differentiation and exhaustion in CAR-T cell therapy
Abstract T cell differentiation is a highly regulated, multi-step process necessary for the progressive establishment of effector functions, immunological memory, and long-term control of pathogens. In response to strong stimulation, as seen in severe or chronic infections or cancer, T cells acquire...
Gardado en:
| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2023-10-01
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| Series: | Journal of Hematology & Oncology |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s13045-023-01504-7 |
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