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Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival

Mammals harbor a limited number of sound-receptor hair cells (HCs) that cannot be regenerated after damage. Thus, investigating the underlying molecular mechanisms that maintain HC survival is crucial for preventing hearing impairment. Intriguingly, Pou4f3-/- or Gfi1-/- HCs form initially but then r...

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Bibliografiske detaljer
Principais autores: Guangqin Wang, Yunpeng Gu, Zhiyong Liu
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2024-03-01
Serier:eLife
Fag:
Online adgang:https://elifesciences.org/articles/90025
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