Contribution of Heptose Metabolites and the cag Pathogenicity Island to the Activation of Monocytes/Macrophages by Helicobacter pylori

The human gastric pathogen Helicobacter pylori activates human epithelial cells by a particular combination of mechanisms, including NOD1 and ALPK1-TIFA activation. These mechanisms are characterized by a strong participation of the bacterial cag pathogenicity island, which forms a type IV secretion...

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Auteurs principaux:	Larissa Faass, Saskia C. Stein, Martina Hauke, Madeleine Gapp, Manuel Albanese, Christine Josenhans
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2021-05-01
Collection:	Frontiers in Immunology
Sujets:	Helicobacter pylori Heptose macrophage secretion system type four secretion system heptose biosynthesis pathway
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.632154/full
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