Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.

<h4>Objective</h4>Previous studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and its relation to coronary heart disease (...

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Detalhes bibliográficos

Principais autores:	Danielle van Keulen, Marianne G Pouwer, Valur Emilsson, Ljubica Perisic Matic, Elsbet J Pieterman, Ulf Hedin, Vilmundur Gudnason, Lori L Jennings, Kim Holmstrøm, Boye Schnack Nielsen, Gerard Pasterkamp, Jan H N Lindeman, Alain J van Gool, Maarten D Sollewijn Gelpke, Hans M G Princen, Dennie Tempel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2019-01-01
coleção:	PLoS ONE
Acesso em linha:	https://doi.org/10.1371/journal.pone.0221477
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