The LEDGIN GS-9822 inhibits HIV-2 infection and enhances HIV-2 latency
ABSTRACT HIV integration is targeted toward active transcription units through the interaction of HIV integrase with the cellular co-factor LEDGF/p75. LEDGINs, small molecule inhibitors of this interaction, reduce HIV-1 integration and retarget residual proviruses away from active transcription unit...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2026-06-01
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| Col·lecció: | Microbiology Spectrum |
| Matèries: | |
| Accés en línia: | https://journals.asm.org/doi/10.1128/spectrum.01699-25 |
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