INFLUENCE OF ANTIBODIES AGAINST CTLA-4 AND PD-1 UPON QUANTITIES OF THEIR TARGET RECEPTORS

Inhibitory receptors CTLA-4 and PD-1 (immune checkpoints) play a key role in regulation of immune reactions. They suppress excessive immune response against pathogenic microbes and prevent autoimmune reactions. The immune checkpoints are targets of the modern effective therapy based on human and hum...

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Główni autorzy:	I. O. Chikileva, I. Zh. Shubina, I. V. Samoylenko, A. V. Karaulov, M. V. Kiselevsky
Format:	Artigo
Język:	Russo
Wydane:	St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2019-01-01
Seria:	Медицинская иммунология
Hasła przedmiotowe:	immune checkpoints inhibitory immune receptors ctla-4 pd-1 ipilimumab nivolumab cancer immunotherapy
Dostęp online:	https://www.mimmun.ru/mimmun/article/view/1699
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