INFLUENCE OF ANTIBODIES AGAINST CTLA-4 AND PD-1 UPON QUANTITIES OF THEIR TARGET RECEPTORS

Inhibitory receptors CTLA-4 and PD-1 (immune checkpoints) play a key role in regulation of immune reactions. They suppress excessive immune response against pathogenic microbes and prevent autoimmune reactions. The immune checkpoints are targets of the modern effective therapy based on human and hum...

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Главные авторы:	I. O. Chikileva, I. Zh. Shubina, I. V. Samoylenko, A. V. Karaulov, M. V. Kiselevsky
Формат:	Artigo
Язык:	Russo
Опубликовано:	St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2019-01-01
Серии:	Медицинская иммунология
Предметы:	immune checkpoints inhibitory immune receptors ctla-4 pd-1 ipilimumab nivolumab cancer immunotherapy
Online-ссылка:	https://www.mimmun.ru/mimmun/article/view/1699
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