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Competence Mining of Vancomycin (VAN) in the Management of Infections Due to Bacterial Strains With High VAN Minimum Inhibitory Concentrations (MICs): A Novel Dosing Strategy Based on Pharmacokinetic/Pharmacodynamic Modeling

The increasing emergence of bacterial strains with high VAN MICs (BSH–VAN–M), such as Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus bovis, results in growing concern that VAN is not effective against these isolates. Due to the limit...

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Principais autores: Xiangqing Song, Meizi Zeng, Yi Wu, Yong Pan
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021-04-01
סדרה:Frontiers in Microbiology
נושאים:
vancomycin
methicillin-resistant Staphylococcus aureus
MRSA
Enterococcus
pharmacokinetic/pharmacodynamic
Monte Carlo simulation
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fmicb.2021.649757/full
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