Competence Mining of Vancomycin (VAN) in the Management of Infections Due to Bacterial Strains With High VAN Minimum Inhibitory Concentrations (MICs): A Novel Dosing Strategy Based on Pharmacokinetic/Pharmacodynamic Modeling

The increasing emergence of bacterial strains with high VAN MICs (BSH–VAN–M), such as Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus bovis, results in growing concern that VAN is not effective against these isolates. Due to the limit...

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Bibliographic Details

Main Authors:	Xiangqing Song, Meizi Zeng, Yi Wu, Yong Pan
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2021-04-01
Series:	Frontiers in Microbiology
Subjects:	vancomycin methicillin-resistant Staphylococcus aureus MRSA Enterococcus pharmacokinetic/pharmacodynamic Monte Carlo simulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.649757/full
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