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A constitutive heterochromatic region shapes genome organization and impacts gene expression in Neurospora crassa

Abstract Background Organization of the eukaryotic genome is essential for proper function, including gene expression. In metazoans, chromatin loops and Topologically Associated Domains (TADs) organize genes into transcription factories, while chromosomes occupy nuclear territories in which silent h...

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Hlavní autoři: Andrew T. Reckard, Abhishek Pandeya, Jacob M. Voris, Carlos G. Gonzalez Cruz, Oluwatosin Oluwadare, Andrew D. Klocko
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-12-01
Edice:BMC Genomics
Témata:
Genome organization
Chromosome conformation
Heterochromatin
Neurospora crassa
Gene expression
On-line přístup:https://doi.org/10.1186/s12864-024-11110-7
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